Pyruvate Dehydrogenase Kinase, Isozyme 1 (PDK1) (Middle Region) Peptide

Details for Product No. ABIN981538, Supplier: Log in to see
Protein Name
  • B830012B01
  • D530020C15Rik
  • si:zfos-979f1.3
  • pyruvate dehydrogenase kinase 1
  • pyruvate dehydrogenase kinase, isoenzyme 1
  • pyruvate dehydrogenase kinase, isozyme 1
  • pyruvate dehydrogenase kinase 1 L homeolog
  • PDK1
  • Pdk1
  • pdk1
  • pdk1.L
Protein Region
Middle Region
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-PDPK1 antibody (3-phosphoinositide Dependent Protein Kinase-1) (Middle Region) (ABIN2777432)
Characteristics This is a synthetic peptide designed for use in combination with anti-PDK1 antibody (Catalog #: ARP31776_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: -

Protein Interaction Partner: AKT1,DLAT,PDHA1,PDK2,RPS6KB1,YWHAQ,DLAT,MTOR,PDK2,PKN1,PKN2,RALGDS,RPS6KB1,RPTOR

Protein Size: 436
Molecular Weight 47 kDa
Gene ID 5163
NCBI Accession NM_002610, NP_002601
UniProt Q15118
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.