Polyhomeotic Homolog 2 (Drosophila) (PhC2) (N-Term) Peptide
PhC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PHC2 (PhC2) products
- PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHC2 Antibody(ARP51251_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))
- Synonyms
- EDR2 Peptide, HPH2 Peptide, PH2 Peptide, A3galt2 Peptide, AA415044 Peptide, D130050K19Rik Peptide, D4Ertd810e Peptide, Edr2 Peptide, Mph2 Peptide, p36 Peptide, cb218 Peptide, edr2 Peptide, id:ibd2745 Peptide, id:ibd5044 Peptide, ph2 Peptide, ph2[a] Peptide, ph2[b] Peptide, ph2alpha Peptide, ph2beta Peptide, phc2 Peptide, wu:fb98c05 Peptide, wu:fc96f07 Peptide, zgc:100775 Peptide, zgc:123102 Peptide, polyhomeotic homolog 2 L homeolog Peptide, polyhomeotic homolog 2 Peptide, polyhomeotic-like 2 (Drosophila) Peptide, polyhomeotic homolog 2a (Drosophila) Peptide, phc2.L Peptide, PHC2 Peptide, Phc2 Peptide, phc2a Peptide
- Background
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In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EDR2, HPH2, MGC163502, PH2
Protein Interaction Partner: MAPKAPK3,AFG3L2,BMI1,BSDC1,FHL3,GFI1B,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1,TMEM70,AFG3L2,BMI1,BSDC1,Bmi1,Cbx2,FHL3,LMO3,MAPKAPK2,MCM2,MCRS1,PHC1,PHC2,RPL7,SCMH1,SFMBT1
Protein Size: 858 - Molecular Weight
- 91 kDa
- Gene ID
- 1912
- NCBI Accession
- NM_198040, NP_932157
- UniProt
- Q8IXK0
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