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Podocalyxin-Like (PODXL) Peptide

PODXL Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN981930
  • Target See all PODXL products
    PODXL (Podocalyxin-Like (PODXL))
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PODXL antibody (Catalog #: ARP44730_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PODXL (Podocalyxin-Like (PODXL))
    Synonyms
    Gp200 Peptide, PC Peptide, PCLP Peptide, PCLP-1 Peptide, PCB Peptide, AW121214 Peptide, Ly102 Peptide, Pclp1 Peptide, podocalyxin Peptide, MEP21 Peptide, PODXL Peptide, Gp135 Peptide, PCLP1 Peptide, cPCLP1 Peptide, podxl Peptide, fc18d02 Peptide, wu:fc18d02 Peptide, Pc Peptide, Pcb Peptide, Podxl Peptide, podocalyxin like Peptide, pyruvate carboxylase Peptide, podocalyxin-like Peptide, PODXL Peptide, PC Peptide, Podxl Peptide, podxl Peptide, Pcx Peptide
    Background
    PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

    Alias Symbols: Gp200, MGC138240, PCLP, PC, PCLP-1

    Protein Interaction Partner: SELL,SLC9A3R2,SELL,SLC9A3R2

    Protein Size: 558
    Molecular Weight
    56 kDa
    Gene ID
    5420
    NCBI Accession
    NM_001018111, NP_001018121
    UniProt
    A6NHX8
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