Podocalyxin-Like (PODXL) Peptide
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- Target See all PODXL products
- PODXL (Podocalyxin-Like (PODXL))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PODXL antibody (Catalog #: ARP44730_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PODXL (Podocalyxin-Like (PODXL))
- Synonyms
- Gp200 Peptide, PC Peptide, PCLP Peptide, PCLP-1 Peptide, PCB Peptide, AW121214 Peptide, Ly102 Peptide, Pclp1 Peptide, podocalyxin Peptide, MEP21 Peptide, PODXL Peptide, Gp135 Peptide, PCLP1 Peptide, cPCLP1 Peptide, podxl Peptide, fc18d02 Peptide, wu:fc18d02 Peptide, Pc Peptide, Pcb Peptide, Podxl Peptide, podocalyxin like Peptide, pyruvate carboxylase Peptide, podocalyxin-like Peptide, PODXL Peptide, PC Peptide, Podxl Peptide, podxl Peptide, Pcx Peptide
- Background
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PODXL is a member of the sialomucin protein family. PODXL was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
Alias Symbols: Gp200, MGC138240, PCLP, PC, PCLP-1
Protein Interaction Partner: SELL,SLC9A3R2,SELL,SLC9A3R2
Protein Size: 558 - Molecular Weight
- 56 kDa
- Gene ID
- 5420
- NCBI Accession
- NM_001018111, NP_001018121
- UniProt
- A6NHX8
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