POU Class 1 Homeobox 1 (POU1F1) Peptide
POU1F1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POU1F1 products
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-POU1F1 antibody (Catalog #: ARP31418_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POU1F1 (POU Class 1 Homeobox 1 (POU1F1))
- Synonyms
- CPHD1 Peptide, GHF-1 Peptide, PIT1 Peptide, POU1F1a Peptide, Pit-1 Peptide, Hmp1 Peptide, Pit1 Peptide, Pit1-rs1 Peptide, dw Peptide, dwarf Peptide, GHF1 Peptide, GHF1A Peptide, PIT1Z Peptide, PIT-1 Peptide, Pit-1* Peptide, pit1 Peptide, pit-1 Peptide, POU class 1 homeobox 1 Peptide, POU domain, class 1, transcription factor 1 Peptide, POU1F1 Peptide, Pou1f1 Peptide, pou1f1 Peptide
- Background
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PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP.
Alias Symbols: PIT1, CPHD1, GHF-1, Pit-1, POU1F1a
Protein Interaction Partner: CREBBP,ETS1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,GATA2,JUN,NR1I2,NR1I3,NR3C1,PITX1,PPARA,PPARG,VDR
Protein Size: 291 - Molecular Weight
- 33 kDa
- Gene ID
- 5449
- NCBI Accession
- NM_000306, NP_000297
- UniProt
- P28069
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