PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1) Peptide
PPFIBP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PPFIBP1 products
- PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PPFIBP1 antibody (Catalog #: ARP42133_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
- Synonyms
- liprin-beta-1 Peptide, L2 Peptide, SGT2 Peptide, hSGT2 Peptide, hSgt2p Peptide, 4632409B19Rik Peptide, AW214454 Peptide, AW261454 Peptide, PPFIA binding protein 1 Peptide, PTPRF interacting protein, binding protein 1 (liprin beta 1) Peptide, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog Peptide, Ppfibp1 Peptide, ppfibp1 Peptide, ppfibp1.S Peptide, PPFIBP1 Peptide
- Background
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PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: L2, hSGT2, hSgt2p, SGT2
Protein Interaction Partner: PPFIA1,PPFIA2,PPFIA3,PPFIBP1,PTPRM,S100A4,YWHAG,PPFIA1,PPFIA2,PPFIBP1,S100A4,SFN,YWHAG,YWHAQ
Protein Size: 170 - Molecular Weight
- 19 kDa
- Gene ID
- 8496
- NCBI Accession
- NM_177444, NP_803193
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