Proteasome Subunit alpha Type 1 (PSMA1) Peptide
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- Target See all PSMA1 products
- PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMA1 antibody (Catalog #: ARP40417_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMA1 (Proteasome Subunit alpha Type 1 (PSMA1))
- Synonyms
- PSMA1 Peptide, pros30 Peptide, DDBDRAFT_0204226 Peptide, DDBDRAFT_0214956 Peptide, DDB_0204226 Peptide, DDB_0214956 Peptide, C2 Peptide, HC2 Peptide, Pros-30 Peptide, alpha-type Peptide, NU Peptide, PROS30 Peptide, CC2 Peptide, zgc:92726 Peptide, 143314_at Peptide, Alpha-6 Peptide, CG4904 Peptide, Dmel\CG4904 Peptide, PROS-35 Peptide, PROS-Dm35 Peptide, Pros-35 Peptide, Pros-Dm35 Peptide, Prosalpha6 Peptide, alpha6 Peptide, alpha_dm Peptide, anon-SAGE:Wang-116 Peptide, pros 35 Peptide, pros35 Peptide, proteasome subunit alpha 1 Peptide, proteasome subunit alpha type 1 Peptide, 20S proteasome subunit C2 Peptide, proteasome (prosome, macropain) subunit, alpha type 1 Peptide, proteasome subunit alpha 1 L homeolog Peptide, Proteasome alpha6 subunit Peptide, PSMA1 Peptide, psma1 Peptide, CNB05540 Peptide, psmA1 Peptide, Psma1 Peptide, psma1.L Peptide, Prosalpha6 Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30
Protein Interaction Partner: C11orf49,CALCOCO2,CCDC85B,CCNH,COIL,KCTD17,KRT15,MCM6,NECAB2,NMI,PLK1,PSMA2,PSMA3,PSMA4,PSMA7,PSMB2,PSMB5,RAD54B,TSC22D4,VIM,C11orf49,CALCOCO2,CCDC85B,CCNH,DLEU1,GIYD2,KCTD17,KRT15,MCM6,NECAB2,NMI,PARK2,PLK1,PSMA3,PSMD13,RAD54B,TSC22D4,VIM
Protein Size: 263 - Molecular Weight
- 29 kDa
- Gene ID
- 5682
- NCBI Accession
- NM_002786, NP_002777
- UniProt
- P25786
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