Proteasome Subunit alpha 6 (PSMA6) Peptide
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- Target See all PSMA6 products
- PSMA6 (Proteasome Subunit alpha 6 (PSMA6))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMA6 antibody (Catalog #: ARP40419_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMA6 (Proteasome Subunit alpha 6 (PSMA6))
- Synonyms
- IOTA Peptide, PROS27 Peptide, p27K Peptide, psma6 Peptide, psma6b Peptide, zgc:91778 Peptide, proteasome subunit alpha 6 Peptide, proteasome (prosome, macropain) subunit, alpha type 6 Peptide, proteasome subunit alpha 6a Peptide, proteasome subunit alpha 6 L homeolog Peptide, proteasome subunit alpha 6, like Peptide, PSMA6 Peptide, Psma6 Peptide, psma6a Peptide, psma6.L Peptide, psma6l Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Protein Interaction Partner: PLK1,PSMA2,PSMA3,PSMA4,PSMA7,GIYD2,PLK1,PSMA3,PSMD13,UBQLN2,USP14,USP53
Protein Size: 246 - Molecular Weight
- 27 kDa
- Gene ID
- 5687
- NCBI Accession
- NM_002791, NP_002782
- UniProt
- P60900
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