Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4) (Middle Region) Peptide
PSMB4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PSMB4 products
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMB4 antibody (Catalog #: ARP56465_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))
- Synonyms
- An18g06680 Peptide, PSMB4 Peptide, Pros-27 Peptide, HN3 Peptide, HsN3 Peptide, PROS-26 Peptide, PROS26 Peptide, im:6909492 Peptide, zgc:110330 Peptide, proteasome subunit beta type-4 Peptide, proteasome subunit beta 4 Peptide, proteasome (prosome, macropain) subunit, beta type 4 Peptide, proteasome subunit beta 4 L homeolog Peptide, ANI_1_890164 Peptide, PSMB4 Peptide, psmb4 Peptide, Psmb4 Peptide, psmb4.L Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB4 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HN3, HsN3, PROS26, PROS-26
Protein Interaction Partner: PLK1,SMAD1,BTBD12,SMAD1
Protein Size: 264 - Molecular Weight
- 29 kDa
- Gene ID
- 5692
- NCBI Accession
- NM_002796, NP_002787
- UniProt
- P28070
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