Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Peptide
PTGS1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all PTGS1 products
- PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PTGS1 antibody (Catalog #: ARP41835_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))
- Synonyms
- COX-1 Peptide, cox-1 Peptide, PTGS1 Peptide, Ptgs1 Peptide, COX1 Peptide, Cox-1 Peptide, Cox-3 Peptide, PGHS-1 Peptide, PHS 1 Peptide, Pghs1 Peptide, Cox1 Peptide, Cox3 Peptide, cox1 Peptide, zCOX-1 Peptide, COX3 Peptide, PCOX1 Peptide, PES-1 Peptide, PGG/HS Peptide, PGHS1 Peptide, PHS1 Peptide, PTGHS Peptide, COX-3 Peptide, prostaglandin-endoperoxide synthase 1 Peptide, cyclooxygenase-1 Peptide, prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) Peptide, prostaglandin-endoperoxide synthase 1 S homeolog Peptide, PTGS1 Peptide, cox-1 Peptide, Ptgs1 Peptide, ptgs1 Peptide, ptgs1.S Peptide
- Background
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Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
Alias Symbols: COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Protein Interaction Partner: PTGS1,NUCB1,PTGS1,NUCB1
Protein Size: 599 - Molecular Weight
- 66 kDa
- Gene ID
- 5742
- NCBI Accession
- NM_000962, NP_000953
- UniProt
- P23219
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