Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) (Middle Region) Peptide
PTPRN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PTPRN products
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EVQQVPSPVS SEPPKAARPP VTPVLLEKKS PLGQSQPTVA GQPSARPAAE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PTPRN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN) peptide
PTPRN Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- Synonyms
- IA-2 Peptide, IA-2/PTP Peptide, IA2 Peptide, ICA512 Peptide, R-PTP-N Peptide, mIA-A Peptide, mKIAA4064 Peptide, Ia-2 Peptide, fc43c04 Peptide, ptprn Peptide, wu:fc43c04 Peptide, ia-2 Peptide, ia2 Peptide, ica512 Peptide, r-ptp-n Peptide, protein tyrosine phosphatase, receptor type N Peptide, protein tyrosine phosphatase, receptor type, N Peptide, protein tyrosine phosphatase, receptor type, Na Peptide, protein tyrosine phosphatase, receptor type N L homeolog Peptide, PTPRN Peptide, Ptprn Peptide, ptprna Peptide, ptprn.L Peptide
- Background
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.
Alias Symbols: IA2, IA-2, ICA512, R-PTP-N, IA-2/PTP
Protein Size: 889 - Molecular Weight
- 66 kDa
- Gene ID
- 5798
- NCBI Accession
- NM_001199763, NP_001186692
- UniProt
- Q16849
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