Regulator of Chromosome Condensation 1 (RCC1) (C-Term) Peptide
RCC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RCC1 products
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RCC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- Synonyms
- Chc1 Peptide, zgc:65796 Peptide, zgc:77114 Peptide, wu:fj77f08 Peptide, rcc1 Peptide, chc1-a Peptide, BJ1 Peptide, CG10480 Peptide, CG18640 (Bj1) Peptide, Dmel\\CG10480 Peptide, RCC1 Peptide, RanGEF Peptide, Rcc1 Peptide, dRCC1 Peptide, inxs Peptide, sdt Peptide, xrcc1 Peptide, chc1-b Peptide, MGC115703 Peptide, MGC132085 Peptide, CHC1 Peptide, RCC1-I Peptide, SNHG3-RCC1 Peptide, 4931417M11Rik Peptide, AI326872 Peptide, regulator of chromosome condensation 1 Peptide, regulator of chromosome condensation 1 L homeolog Peptide, Regulator of chromosome condensation 1 Peptide, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted Peptide, regulator of chromosome condensation 1 S homeolog Peptide, rcc1 Peptide, RCC1 Peptide, rcc1.L Peptide, Rcc1 Peptide, rcc1.S Peptide
- Background
-
RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
Protein Interaction Partner: CDK1,CHKA,CSNK1A1,HIST2H2AA3,HIST2H2BE,KPNA3,NUP98,PTMA,RAN,RANBP1,RANBP3,RCC1,XPO1,CSNK1A1,DIS3,H2AFY,KPNA3,KPNA4,KPNB1,METTL11A,RAN,RANBP3,TAL1,XPO1
Protein Size: 421 - Molecular Weight
- 45 kDa
- Gene ID
- 1104
- NCBI Accession
- NM_001269, NP_001260
- UniProt
- P18754
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