Retinol Dehydrogenase 8 (RDH8) (Middle Region) Peptide
RDH8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RDH8 products
- RDH8 (Retinol Dehydrogenase 8 (RDH8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FDTNFFGAVR LVKAVLPGMK RRRQGHIVVI SSVMGLQGVI FNDVYAASKF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RDH8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RDH8 (Retinol Dehydrogenase 8 (RDH8))
- Synonyms
- PRRDH Peptide, SDR28C2 Peptide, Gm182 Peptide, prRDH Peptide, cb501 Peptide, rdh8 Peptide, zf1.1 Peptide, zfprRDH2 Peptide, zgc:73081 Peptide, retinol dehydrogenase 8 (all-trans) Peptide, retinol dehydrogenase 8 Peptide, retinol dehydrogenase 8a Peptide, RDH8 Peptide, Rdh8 Peptide, rdh8a Peptide, MCYG_01756 Peptide, MGYG_04308 Peptide, rdh8 Peptide
- Background
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All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors, hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin.
Alias Symbols: PRRDH, SDR28C2
Protein Size: 311 - Molecular Weight
- 34 kDa
- Gene ID
- 50700
- NCBI Accession
- NM_015725, NP_056540
- UniProt
- Q9NYR8
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