Replication Factor C (Activator 1) 1, 145kDa (RFC1) (Middle Region) Peptide
RFC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RFC1 products
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AQAIYASVLP GELMRGYMTQ FPTFPSWLGK HSSTGKHDRI VQDLALHMSL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RFC1 Antibody(ARP56522_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- Synonyms
- A1 Peptide, MHCBFB Peptide, PO-GA Peptide, RECC1 Peptide, RFC Peptide, RFC140 Peptide, AtRFC1 Peptide, replication factor C 1 Peptide, replication factor C1 Peptide, 140kDa Peptide, Alp145 Peptide, Recc1 Peptide, Replication factor C1 Peptide, si:dkey-170e5.1 Peptide, zgc:162875 Peptide, replication factor C subunit 1 Peptide, replication factor C1 Peptide, replication factor C (activator 1) 1 Peptide, DNA replication factor C complex subunit Rfc1 Peptide, RFC1 Peptide, Rfc1 Peptide, rfc1 Peptide
- Background
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The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.
Alias Symbols: A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Protein Interaction Partner: BRCA1,BRD4,CASP3,CCND1,CDK4,CEBPA,HDAC1,MYOC,PCNA,RELA,RFC1,RFC2,RFC3,SMC1A,TCEAL1,ATM,BLM,BRCA1,BRD4,CCND1,CDK4,CHTF18,HDAC1,KIT,MLH1,MRE11A,MSH2,MSH6,NBN,PCNA,PMS1,RAD17,RAD50,RB1,RELA,RFC2,RFC3,RFC4,RFC5,SMARCA4,SSBP3,TP53,XRCC5,ZSCAN1
Protein Size: 1147 - Molecular Weight
- 128 kDa
- Gene ID
- 5981
- NCBI Accession
- NM_002913, NP_002904
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