Replication Factor C (Activator 1) 1, 145kDa (RFC1) (C-Term) Peptide
RFC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RFC1 products
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LNEDDSQSDE KDQDAIETDA MIKKKTKSSK PSKPEKDKEP RKGKGKSSKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- RFC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))
- Synonyms
- A1 Peptide, MHCBFB Peptide, PO-GA Peptide, RECC1 Peptide, RFC Peptide, RFC140 Peptide, AtRFC1 Peptide, replication factor C 1 Peptide, replication factor C1 Peptide, 140kDa Peptide, Alp145 Peptide, Recc1 Peptide, Replication factor C1 Peptide, si:dkey-170e5.1 Peptide, zgc:162875 Peptide, replication factor C subunit 1 Peptide, replication factor C1 Peptide, replication factor C (activator 1) 1 Peptide, DNA replication factor C complex subunit Rfc1 Peptide, RFC1 Peptide, Rfc1 Peptide, rfc1 Peptide
- Background
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This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: A1, RFC, PO-GA, RECC1, MHCBFB, RFC140
Protein Size: 1148 - Gene ID
- 5981
- NCBI Accession
- NM_001204747, NP_001191676
- UniProt
- P35251
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