RING Finger Protein 6 (RNF6) (N-Term) Peptide
RNF6
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RNF6 products
- RNF6 (RING Finger Protein 6 (RNF6))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RNF6 antibody (Catalog #: ARP43064_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RNF6 (RING Finger Protein 6 (RNF6))
- Synonyms
- 1200013I08Rik Peptide, 5730419H05Rik Peptide, AA537053 Peptide, ring finger protein 6 Peptide, ring finger protein (C3H2C3 type) 6 Peptide, RNF6 Peptide, Rnf6 Peptide
- Background
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RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Alias Symbols: DKFZp686P0776
Protein Size: 685 - Molecular Weight
- 78 kDa
- Gene ID
- 6049
- NCBI Accession
- NM_005977, NP_005968
- UniProt
- Q9Y252
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