Ribosomal Protein L5 (RPL5) (N-Term) Peptide
-
- Target See all RPL5 products
- RPL5 (Ribosomal Protein L5 (RPL5))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RPL5 antibody (Catalog #: ARP56125_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- RPL5 (Ribosomal Protein L5 (RPL5))
- Synonyms
- DBA6 Peptide, L5 Peptide, U21RNA Peptide, CG17489 Peptide, Dmel\\CG17489 Peptide, E-2d Peptide, M(2)40B Peptide, Rp L5 Peptide, Rpl5 Peptide, dRPL5 Peptide, yip6 Peptide, rpl5 Peptide, wu:fj02g05 Peptide, zgc:86854 Peptide, mg:cb01f08 Peptide, rpl5l Peptide, zgc:56511 Peptide, zgc:77176 Peptide, ribosomal protein L5 Peptide, 60S ribosomal protein L5 Peptide, Ribosomal protein L5 Peptide, ribosomal protein L5 L homeolog Peptide, 50S ribosomal protein L5 Peptide, ribosomal protein L5 S homeolog Peptide, ribosomal protein L5b Peptide, rpl5 Peptide, ribosomal protein L5a Peptide, Rpl5 Peptide, RPL5 Peptide, rpl-5 Peptide, RpL5 Peptide, rpl5.L Peptide, rpl5 Peptide, rpl5.S Peptide, rpl5b Peptide, rpl5a Peptide
- Background
-
RPL5 is required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC117339, MSTP030, L5, DBA6
Protein Interaction Partner: CSNK2A1,CSNK2B,EIF5A,HARS,IPO5,IPO7,KPNB1,MAP3K14,MDM2,NVL,PDCD4,PPM1D,RPL5,TNIP1,TNPO1,UPF2,AMFR,CSNK2A1,CSNK2B,EIF5A,IPO13,MDM2,PDCD4,RPL5,RRP1B,Rrp1b
Protein Size: 297 - Molecular Weight
- 34 kDa
- Gene ID
- 6125
- NCBI Accession
- NM_000969, NP_000960
- UniProt
- P46777
-