Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide
RUNX1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RUNX1 products
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RUNX1 antibody (Catalog #: P100904_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- Synonyms
- RUNX1 Peptide, runx1 Peptide, AI462102 Peptide, AML1 Peptide, Cbfa2 Peptide, Pebp2a2 Peptide, Pebpa2b Peptide, AML1-EVI-1 Peptide, AMLCR1 Peptide, CBFA2 Peptide, EVI-1 Peptide, PEBP2aB Peptide, runxa Peptide, Runx-1 Peptide, XAML Peptide, Xaml1 Peptide, aml Peptide, aml-1 Peptide, aml1 Peptide, aml1-evi-1 Peptide, amlcr1 Peptide, cbfa2 Peptide, evi-1 Peptide, pebp2ab Peptide, Aml1 Peptide, uncharacterized LOC473981 Peptide, runt-related transcription factor Peptide, runt related transcription factor 1 Peptide, runt-related transcription factor 1 Peptide, runt related transcription factor 1 L homeolog Peptide, LOC473981 Peptide, runt Peptide, Runx1 Peptide, RUNX1 Peptide, runx1 Peptide, runx1.L Peptide
- Background
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2aB
Protein Interaction Partner: CBFB,TLE1,CBFB,TLE1,AR,CBFA2T2,CBFA2T3,CBFB,CCND1,CCND2,CCND3,CDK6,CEBPA,CEBPB,ELF2,ELF4,EP300,FOS,FOXP3,HIPK1,HIPK2,JUN,MYST3,MYST4,NCOR2,PAX5,SUV39H1,TLE1,TLE2,WWTR1,YAP1,AES,CBFA2T2,CBFB,CEBPB,EFNA2,ELF2,ELF4,ETS1,FHL2,FOS,JUN,LEF1,MYOD1,MYST4,PAX5,SMAD1,SMAD2,SMAD3,SMAD5,SUV39H1,TLE1,TRAF6,VDR,YAP1
Protein Size: 480 - Molecular Weight
- 52 kDa
- Gene ID
- 861
- NCBI Accession
- NM_001754, NP_001745
- UniProt
- B2RMS4
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