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Sirtuin 2 (SIRT2) Peptide

SIRT2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983764
  • Target See all SIRT2 products
    SIRT2 (Sirtuin 2 (SIRT2))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SIRT2 antibody (Catalog #: ARP32385_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIRT2 (Sirtuin 2 (SIRT2))
    Synonyms
    CG5085 Peptide, D.mel2 Peptide, Dmel\\CG5085 Peptide, SIRT2 Peptide, dSIRT2 Peptide, sir2 Peptide, Sirt2 Peptide, BmSirt2 Peptide, AtSRT2 Peptide, SIRTUIN 2 Peptide, T2K12.8 Peptide, sirtuin 2 Peptide, SIR2 Peptide, SIR2L Peptide, SIR2L2 Peptide, 5730427M03Rik Peptide, Sir2l Peptide, wu:fb57d05 Peptide, zgc:55966 Peptide, zgc:77003 Peptide, Sirtuin 2 Peptide, sirtuin 2 Peptide, sirtuin 2 S homeolog Peptide, NAD-dependent deacetylase sirtuin 2 homolog Peptide, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) Peptide, Sirt2 Peptide, SIRT2 Peptide, sirt2.S Peptide, SRT2 Peptide, sirt2 Peptide
    Background
    SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.

    Alias Symbols: SIR2, SIR2L, SIR2L2

    Protein Interaction Partner: CDC14B,HDAC6,HOXA10,KAT2A,KAT2B,SP140,TUBA4A,DNAJB6,DNAJB8,ELL,GYS1,KRT78,PHB2,RTN4,SARS,SPOP,TUBB

    Protein Size: 352
    Molecular Weight
    40 kDa
    Gene ID
    22933
    NCBI Accession
    NM_030593, NP_085096
    UniProt
    Q8IXJ6
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