Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) (N-Term) Peptide
SLC7A5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SLC7A5 products
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MAGAGPKRRA LAAPAAEEKE EAREKMLAAK SADGSAPAGE GEGVTLQRNI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SLC7A5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) peptide
SLC7A5 Reactivity: Human, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
- Synonyms
- 4F2LC Peptide, CD98 Peptide, D16S469E Peptide, E16 Peptide, LAT1 Peptide, MPE16 Peptide, hLAT1 Peptide, D0H16S474E Peptide, TA1 Peptide, JHI-21 Peptide, SLC7A5 Peptide, LAT-1 Peptide, slc7a5a Peptide, 4F2 Peptide, 4F2HC Peptide, AI314110 Peptide, Cd98 Peptide, Ly-10 Peptide, Ly-m10 Peptide, Ly10 Peptide, Mdu1 Peptide, Mgp-2hc Peptide, NACAE Peptide, solute carrier family 7 member 5 Peptide, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Peptide, solute carrier family 7 (amino acid transporter light chain, L system), member 5 Peptide, solute carrier family 7 member 5 S homeolog Peptide, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Peptide, SLC7A5 Peptide, Slc7a5 Peptide, slc7a5.S Peptide, Slc3a2 Peptide
- Background
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SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.
Alias Symbols: 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1
Protein Interaction Partner: SLC3A2,SLC3A2,UBC
Protein Size: 507 - Molecular Weight
- 56 kDa
- Gene ID
- 8140
- NCBI Accession
- NM_003486, NP_003477
- UniProt
- Q01650
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