Structural Maintenance of Chromosomes 2 (SMC2) (Middle Region) Peptide
SMC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SMC2 products
- SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMC2 antibody (Catalog #: ARP46156_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
- Synonyms
- CAP-E Peptide, CAPE Peptide, SMC-2 Peptide, SMC2L1 Peptide, 5730502P04Rik Peptide, AI255214 Peptide, AW545314 Peptide, Fin16 Peptide, Smc2l1 Peptide, fb92e05 Peptide, wu:fb92e05 Peptide, zeh1628 Peptide, zgc:55326 Peptide, xcap-e Peptide, SCII Peptide, structural maintenance of chromosomes 2 Peptide, structural maintenance of chromosomes 2 L homeolog Peptide, SMC2 Peptide, Smc2 Peptide, smc2 Peptide, smc2.L Peptide
- Background
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SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAP-E, CAPE, FLJ10093, SMC2L1, hCAP-E
Protein Interaction Partner: LIG4,NCAPD2,SMC4,CASP4,DNMT3B,NCAPD2,PTP4A3,SMC4
Protein Size: 1197 - Molecular Weight
- 136 kDa
- Gene ID
- 10592
- NCBI Accession
- NM_006444, NP_006435
- UniProt
- O95347
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