Serum Response Factor (SRF) Peptide
SRF
Reactivity: Human, Mouse
Host: Synthetic
BP, ChIP, WB
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- Target See all SRF products
- SRF (Serum Response Factor (SRF))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Chromatin Immunoprecipitation (ChIP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SRF antibody (Catalog #: P100866_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SRF (Serum Response Factor (SRF))
- Synonyms
- AW049942 Peptide, AW240594 Peptide, MCM1 Peptide, SRFX Peptide, XSRF Peptide, srf-A Peptide, RGD1559787 Peptide, srf Peptide, srf1 Peptide, serum response factor Peptide, serum response factor L homeolog Peptide, serum response factor a Peptide, Srf Peptide, SRF Peptide, srf.L Peptide, srfa Peptide
- Background
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SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Alias Symbols: MCM1
Protein Interaction Partner: FHL1,FHL2,FHL3,FHL5,FOS,FOSL1,NFYA,ATF6,BARX2,CAMK2A,CASP3,CASP6,CASP7,CASP8,CASP9,CEBPB,CREB1,CREBBP,CRIP2,CSNK2A1,ELK1,ELK4,ETV4,FHL1,FHL2,FHL3,FHL5,FLI1,GATA4,GTF2F1,GTF2I,HMGA1,HOPX,MAPKAPK2,MINPP1,MKL1,MKL2,MYOCD,MYOD1,MYOG,NCOA1,NCOR2,NFYA,NKX2-3,NKX2-5,NKX3-1,OGT,PML,PRKDC,PRRX1,PYCARD,RELA,RPS6KA1,RXRA,RXRG,SRC,SRF,SRFBP1,SSRP1,TCF3,TEAD1,ASCC1,ASCC2,ASCC3,ATF6,CD63,CEBPB,CREBBP,ELK1,ELK4,FLI1,GATA4,GTF2F1,GTF2I,Gata2,Gata4,Gata6,Hmga1,Hmga2,MKL1,MKL2,MYOCD,MYOG,Mkl1,Mkl2,Myocd,NCOA6,NCOR2,NFYA,NKX3-1,Nkx2-5,PML,RARG,REL,RELA,RXRG,SMARCA4,SP1,SRC,SSRP1,Ssrp1,TEAD1
Protein Size: 508 - Molecular Weight
- 52 kDa
- Gene ID
- 6722
- NCBI Accession
- NM_003131, NP_003122
- UniProt
- P11831
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