Synovial Sarcoma, X Breakpoint 4B (SSX4B) (Middle Region) Peptide
SSX4B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SSX4B products
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SSX4B Antibody(ARP50423_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
- Synonyms
- CT5.4 Peptide, SSX family member 4B Peptide, SSX4B Peptide
- Background
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The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: SSX4, CT5.4
Protein Interaction Partner: HIF1A
Protein Size: 188 - Molecular Weight
- 22 kDa
- Gene ID
- 548313
- NCBI Accession
- NM_001034832, NP_001030004
- UniProt
- O60224
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