Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM) (N-Term) Peptide
STAM
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STAM products
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EQAKASPALV AKDPGTVANK KEEEDLAKAI ELSLKEQRQQ STTLSTLYPS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STAM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
- Synonyms
- STAM-1 Peptide, STAM1 Peptide, wu:fv75b10 Peptide, zgc:55725 Peptide, RGD1564499 Peptide, signal transducing adaptor molecule Peptide, signal transducing adapter molecule 1 Peptide, Signal transducing adapter molecule 1 Peptide, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 Peptide, STAM Peptide, CpipJ_CPIJ003516 Peptide, Tsp_03939 Peptide, stam-1 Peptide, Stam Peptide, stam Peptide
- Background
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This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.
Alias Symbols: DKFZp686J2352, STAM1, STAM-1
Protein Interaction Partner: HGS,JAK1,JAK2,JAK3,PPP1CA,STAMBP,TIMM8A,USP8,CLTC,HGS,JAK2,JAK3,STAMBP,TIMM8A,UBC,UBI4,USP8
Protein Size: 540 - Molecular Weight
- 59 kDa
- Gene ID
- 8027
- NCBI Accession
- NM_003473, NP_003464
- UniProt
- Q92783
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