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Stanniocalcin 1 (STC1) (N-Term) Peptide

STC1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN984544
  • Target See all Stanniocalcin 1 (STC1) products
    Stanniocalcin 1 (STC1)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-STC1 antibody (Catalog #: ARP42104_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Stanniocalcin 1 (STC1)
    Synonyms
    STC Peptide, Stc Peptide, stc1 Peptide, MGC82280 Peptide, STC1 Peptide, zgc:153307 Peptide, LOC777959 Peptide, stanniocalcin 1 Peptide, stanniocalcin 1 L homeolog Peptide, stanniocalcin 1 S homeolog Peptide, STC1 Peptide, Stc1 Peptide, stc1.L Peptide, stc1.S Peptide, stc1 Peptide, LOC777959 Peptide
    Background
    STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. It contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: STC

    Protein Size: 247
    Molecular Weight
    26 kDa
    Gene ID
    6781
    NCBI Accession
    NM_003155, NP_003146
    UniProt
    P52823
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