TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C) (N-Term) Peptide
TAF1C
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all TAF1C products
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TAF1C antibody (Catalog #: ARP57920_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAF1C (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa (TAF1C))
- Synonyms
- TAF1C Peptide, Tafi95 Peptide, mTAFI95 Peptide, MGC:39976 Peptide, SL1 Peptide, TAFI110 Peptide, TAFI95 Peptide, TATA-box binding protein associated factor, RNA polymerase I subunit C Peptide, TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa Peptide, TATA-box binding protein associated factor, RNA polymerase I, C Peptide, TATA-box binding protein associated factor, RNA polymerase 1 subunit C Peptide, TAF1C Peptide, Taf1c Peptide
- Background
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Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
Alias Symbols: MGC:39976, SL1, TAFI110, TAFI95
Protein Interaction Partner: TAF1A,TAF1B,TBP,POLR1E,RRN3,TAF1A,TAF1B,TBP,TP53,TRIM24,CD3EAP,MYC,RRN3,RRN3,TAF1A,TAF1B,TAF1D,TBP,TP53,UBTF
Protein Size: 869 - Molecular Weight
- 95 kDa
- Gene ID
- 9013
- NCBI Accession
- NM_005679, NP_005670
- UniProt
- Q15572
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