TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L) Peptide
TAF5L
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TAF5L products
- TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TAF5L antibody (Catalog #: ARP32566_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAF5L (TAF5-Like RNA Polymerase II, P300/CBP-Associated Factor (PCAF)-Associated Factor, 65kDa (TAF5L))
- Synonyms
- PAF65B Peptide, taf5l Peptide, MGC89568 Peptide, fi28g02 Peptide, wu:fi28g02 Peptide, zgc:63765 Peptide, 1110005N04Rik Peptide, AI849020 Peptide, TATA-box binding protein associated factor 5 like Peptide, TATA-box binding protein associated factor 5 like L homeolog Peptide, PCAF associated factor 65 beta Peptide, TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor Peptide, TAF5L Peptide, taf5l.L Peptide, taf5l Peptide, PY07202 Peptide, Taf5l Peptide
- Background
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF5L encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF5. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.
Alias Symbols: PAF65B
Protein Interaction Partner: ATXN7L3,KAT2B,MYC,SUPT3H,TAF10,TAF9,USP22
Protein Size: 589 - Molecular Weight
- 66 kDa
- Gene ID
- 27097
- NCBI Accession
- NM_014409, NP_055224
- UniProt
- O75529
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