Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1) (Middle Region) Peptide
TAP1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all TAP1 products
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TAP1 antibody (Catalog #: ARP43628_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))
- Synonyms
- ABC17 Peptide, ABCB2 Peptide, APT1 Peptide, D6S114E Peptide, PSF-1 Peptide, PSF1 Peptide, RING4 Peptide, TAP1*0102N Peptide, TAP1N Peptide, abc17 Peptide, abcb2 Peptide, apt1 Peptide, psf1 Peptide, ring4 Peptide, tap1a Peptide, tap1n Peptide, Abcb2 Peptide, Ham-1 Peptide, Ham1 Peptide, MTP1 Peptide, TAP Peptide, Tap-1 Peptide, Y3 Peptide, Cim Peptide, transporter 1, ATP binding cassette subfamily B member Peptide, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog Peptide, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Peptide, TAP1 Peptide, tap1.L Peptide, Tap1 Peptide
- Background
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N, PSF-1
Protein Interaction Partner: ESR1,HLA-F,HLA-G,KRTAP4-12,MDFI,PDIA3,PSMB5,PSMB8,TAP2,TAPBP,COPB1,COPG,HLA-A,HLA-G,KRTAP4-12,MDFI,PDIA3,TAP2,TAPBP
Protein Size: 808 - Molecular Weight
- 87 kDa
- Gene ID
- 6890
- NCBI Accession
- NM_000593, NP_000584
- UniProt
- Q03518
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