T-Box 5 (TBX5) Peptide
TBX5
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all T-Box 5 (TBX5) products
- T-Box 5 (TBX5)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TBX5 antibody (Catalog #: ARP33403_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- T-Box 5 (TBX5)
- Synonyms
- TBX5 Peptide, tbx-5 Peptide, xtbx-5 Peptide, xtbx5 Peptide, tbx5 Peptide, HOS Peptide, tbx5.1 Peptide, zTbx5 Peptide, zf-tbx5 Peptide, T-box 5 Peptide, T-box 5 L homeolog Peptide, T-box 5a Peptide, TBX5 Peptide, tbx5 Peptide, tbx5.L Peptide, Tbx5 Peptide, tbx5a Peptide
- Background
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TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: HOS
Protein Interaction Partner: GATA4,NKX2-5,GATA4,NKX2-5
Protein Size: 518 - Molecular Weight
- 58 kDa
- Gene ID
- 6910
- NCBI Accession
- NM_000192, NP_000183
- UniProt
- Q99593
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