Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3) Peptide
-
- Target See all TCEB3 products
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCEB3 antibody (Catalog #: P100692_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))
- Synonyms
- CG6755 Peptide, Dmel\\CG6755 Peptide, Elo-A Peptide, dEloA Peptide, tceb3a Peptide, zgc:56638 Peptide, wu:fw66g10 Peptide, TCEB3 Peptide, 110kDa Peptide, AA408125 Peptide, Tceb3a Peptide, El Peptide, EloA Peptide, SIII Peptide, SIII p110 Peptide, TCEB3A Peptide, Elongin A Peptide, transcription elongation factor B polypeptide 3 Peptide, elongin A Peptide, calcium binding and coiled-coil domain 1b Peptide, elongin A S homeolog Peptide, transcription elongation factor B subunit 3 Peptide, EloA Peptide, LOC413407 Peptide, eloa Peptide, calcoco1b Peptide, ELOA Peptide, eloa.S Peptide, Eloa Peptide, TCEB3 Peptide
- Background
-
Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Alias Symbols: EloA, SIII, TCEB3A, SIII p110
Protein Interaction Partner: MED21,NINL,RAP1A,REXO1,TCEB2,NINL,SOCS1,TCEB1,TCEB2
Protein Size: 772 - Molecular Weight
- 87 kDa
- Gene ID
- 6924
- NCBI Accession
- NM_003198, NP_003189
- UniProt
- Q14241
-