Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP) (Middle Region) Peptide
TERF2IP
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all RAP1 (TERF2IP) products
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTYVKENARS PSSVTGNALW KAMEKSSLTQ HSWQSLKDRY LKHLRGQEHK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Terf2ip Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RAP1 (TERF2IP) (Telomeric Repeat Binding Factor 2, Interacting Protein (TERF2IP))
- Synonyms
- DRIP5 Peptide, RAP1 Peptide, Rap1 Peptide, cRAP1 Peptide, TERF2 interacting protein Peptide, telomeric repeat binding factor 2, interacting protein Peptide, TERF2IP Peptide, Terf2ip Peptide
- Background
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Terf2ip acts both as a regulator of telomere function and as a transcription regulator. It is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
Alias Symbols: Rap1
Protein Size: 286 - Molecular Weight
- 31 kDa
- Gene ID
- 57321
- NCBI Accession
- NM_020584, NP_065609
- UniProt
- Q91VL8
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