Transcription Factor Dp-1 (TFDP1) (N-Term) Peptide
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- Target See all DP1 (TFDP1) products
- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NLSPGKGVVS LVAVHPSTVN TLGKQLLPKT FGQSNVNITQ QVVIGTPQRP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Tfdp1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DP1 (TFDP1) (Transcription Factor Dp-1 (TFDP1))
- Synonyms
- tfdp1l Peptide, wu:fb94b07 Peptide, wu:fc52a06 Peptide, zgc:55487 Peptide, DP1 Peptide, DRTF1 Peptide, Dp-1 Peptide, Dp1 Peptide, Drtf1 Peptide, TFDP1 Peptide, dp-1 Peptide, dp1 Peptide, drtf1 Peptide, tfdp1 Peptide, tfdp1a Peptide, transcription factor Dp-1, a Peptide, transcription factor Dp-1 Peptide, transcription factor Dp 1 Peptide, transcription factor Dp-1 pseudogene Peptide, transcription factor Dp-1 L homeolog Peptide, tfdp1a Peptide, TFDP1 Peptide, Tfdp1 Peptide, LOC465967 Peptide, tfdp1.L Peptide, tfdp1 Peptide, PITG_20195 Peptide, Tsp_02025 Peptide, LOC100457325 Peptide
- Background
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Tfdp1 can stimulate E2F-dependent transcription. Tfdp1 binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F-1/DP complex appears to mediate both cell proliferation and apoptosis.
Alias Symbols: Dp1, Drtf1
Protein Interaction Partner: E2F6,Epc1
Protein Size: 410 - Molecular Weight
- 45 kDa
- Gene ID
- 21781
- NCBI Accession
- NM_009361, NP_033387
- UniProt
- Q08639
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