Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) (C-Term) Peptide
TFPI
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TFPI products
- TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PFKYSGCGGN ENNFTSKQEC LRACKKGFIQ RISKGGLIKT KRKRKKQRVK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TFPI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI) peptide
TFPI Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))
- Synonyms
- EPI Peptide, LACI Peptide, TFI Peptide, TFPI1 Peptide, A630013F22Rik Peptide, AW552122 Peptide, TFPI Peptide, si:dz44f8.1 Peptide, tfpib Peptide, wu:fb92g01 Peptide, zgc:152844 Peptide, zgc:158592 Peptide, tissue factor pathway inhibitor Peptide, tissue factor pathway inhibitor a Peptide, TFPI Peptide, Tfpi Peptide, tfpia Peptide
- Background
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This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.
Alias Symbols: EPI, LACI, TFI, TFPI1
Protein Interaction Partner: ELANE,F10,MMP1,MMP12,MMP7,MMP8,MMP9,PRSS3,THBS1,F10,PRSS3,THBS1
Protein Size: 304 - Molecular Weight
- 33 kDa
- Gene ID
- 7035
- NCBI Accession
- NM_006287, NP_006278
- UniProt
- P10646
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