TIMP Metallopeptidase Inhibitor 3 (TIMP3) (N-Term) Peptide
-
- Target See all TIMP3 products
- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MTPWLGLIVL LGSWSLGDWG AEACTCSPSH PQDAFCNSDI VIRAKVVGKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TIMP3 Antibody,. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
- Synonyms
- TIMP-3 Peptide, TIMP3 Peptide, timp3 Peptide, HSMRK222 Peptide, K222 Peptide, K222TA2 Peptide, SFD Peptide, IMP-3 Peptide, timp3-A Peptide, Timp-3 Peptide, metalloproteinase inhibitor 3 Peptide, TIMP metallopeptidase inhibitor 3 Peptide, Metalloproteinase inhibitor 3 Peptide, TIMP metallopeptidase inhibitor 3 L homeolog Peptide, tissue inhibitor of metalloproteinase 3 Peptide, CpipJ_CPIJ003282 Peptide, TIMP3 Peptide, timp3 Peptide, Timp3 Peptide, timp3.L Peptide
- Background
-
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Alias Symbols: HSMRK222, K222, K222TA2, SFD
Protein Interaction Partner: ADAM17,EFEMP1,KDR,MMP13,MMP14,MMP2,MMP3,MMP9,ADAM17,MMP2
Protein Size: 211 - Molecular Weight
- 22 kDa
- Gene ID
- 7078
- NCBI Accession
- NM_000362, NP_000353
- UniProt
- P35625
-