Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6) (C-Term) Peptide
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- Target See all TNFAIP6 products
- TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DIISTGNVMT LKFLSDASVT AGGFQIKYVA MDPVSKSSQG KNTSTTSTGN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFAIP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))
- Synonyms
- Tnfip6 Peptide, TSG-6 Peptide, Tsg6 Peptide, TSG6 Peptide, TNF alpha induced protein 6 Peptide, tumor necrosis factor alpha induced protein 6 Peptide, Tnfaip6 Peptide, TNFAIP6 Peptide
- Background
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The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Alias Symbols: TSG-6, TSG6
Protein Interaction Partner: ACAN,THBS1,ACAN
Protein Size: 277 - Molecular Weight
- 30 kDa
- Gene ID
- 7130
- NCBI Accession
- NM_007115, NP_009046
- UniProt
- P98066
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