Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9) (C-Term) Peptide
TNFRSF9
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CD137 (TNFRSF9) products
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTLRFSVVKR GRKKLLYIFK QPFMRPVQTT QEEDGCSCRF PEEEEGGCEL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFRSF9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
- Synonyms
- TNFRSF9 Peptide, zgc:136557 Peptide, 4-1BB Peptide, CD137 Peptide, CDw137 Peptide, ILA Peptide, A930040I11Rik Peptide, AA408498 Peptide, AI325004 Peptide, Cd137 Peptide, Ly63 Peptide, tumor necrosis factor receptor superfamily member 9 Peptide, TNF receptor superfamily member 9 Peptide, tumor necrosis factor receptor superfamily, member 9a Peptide, tumor necrosis factor receptor superfamily, member 9 Peptide, TNFRSF9 Peptide, tnfrsf9a Peptide, Tnfrsf9 Peptide
- Background
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Alias Symbols: 4-1BB, CD137, CDw137, ILA, MGC2172
Protein Interaction Partner: LRR1,TNFRSF4,TNFSF9,TRAF1,TRAF2,TRAF3,TNFRSF9,TRAF1,TRAF2,TRAF3
Protein Size: 255 - Molecular Weight
- 26 kDa
- Gene ID
- 3604
- NCBI Accession
- NM_001561, NP_001552
- UniProt
- Q07011
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