Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) (Middle Region) Peptide
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- Target See all TNFSF13 products
- TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EQSSDALEAW ENGERSRKRR AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFSF13 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))
- Synonyms
- APRIL Peptide, CD256 Peptide, TALL-2 Peptide, TALL2 Peptide, TRDL-1 Peptide, ZTNF2 Peptide, 2310026N09Rik Peptide, April Peptide, Tall2 Peptide, Trdl1 Peptide, SLAN Peptide, ANP32B Peptide, april Peptide, tnf13 Peptide, TNLG7B Peptide, TNF superfamily member 13 Peptide, tumor necrosis factor (ligand) superfamily, member 13 Peptide, acidic leucine-rich nuclear phosphoprotein 32 family member B Peptide, TNFSF13 Peptide, Tnfsf13 Peptide, LOC494442 Peptide, tnfsf13 Peptide
- Background
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The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Alias Symbols: APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand, ZTNF2, TALL-2
Protein Interaction Partner: FAS,FURIN,SDC2,TNFRSF11B,TNFRSF13B,TNFRSF14,TNFRSF17,TNFRSF1A,TNFSF13B,FAS,TNFRSF11B,TNFRSF13B,TNFRSF14,TNFRSF17,TNFRSF1A,TNFSF13,TNFSF13B
Protein Size: 250 - Molecular Weight
- 16 kDa
- Gene ID
- 8741
- NCBI Accession
- NM_003808, NP_003799
- UniProt
- O75888
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