Tryptophan Hydroxylase 2 (TPH2) Peptide
Quick Overview for Tryptophan Hydroxylase 2 (TPH2) Peptide (ABIN985410)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TPH2 antibody (Catalog #: ARP34141_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Tryptophan Hydroxylase 2 (TPH2)
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Background
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Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.
Alias Symbols: NTPH, ADHD7
Protein Size: 490 -
Molecular Weight
- 56 kDa
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Gene ID
- 121278
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NCBI Accession
- NM_173353, NP_775489
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UniProt
- Q8IWU9
Target
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