Tripartite Motif Containing 22 (TRIM22) Peptide
TRIM22
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRIM22 products
- TRIM22 (Tripartite Motif Containing 22 (TRIM22))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM22 antibody (Catalog #: P100888_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIM22 (Tripartite Motif Containing 22 (TRIM22))
- Synonyms
- GPSTAF50 Peptide, RNF94 Peptide, STAF50 Peptide, tripartite motif containing 22 Peptide, TRIM22 Peptide
- Background
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TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPSTAF50, RNF94, STAF50
Protein Interaction Partner: CIC,RERE,USP7
Protein Size: 498 - Molecular Weight
- 57 kDa
- Gene ID
- 10346
- NCBI Accession
- NM_006074, NP_006065
- UniProt
- Q8IYM9
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