Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3) (N-Term) Peptide
TRPC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRPC3 products
- TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRPC3 antibody (Catalog #: ARP58715_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRPC3 (Transient Receptor Potential Cation Channel, Subfamily C, Member 3 (TRPC3))
- Synonyms
- TRPC3 Peptide, Trpc3 Peptide, TRP3 Peptide, Mwk Peptide, Trcp3 Peptide, Trp3 Peptide, Trrp3 Peptide, TrpC3c Peptide, transient receptor potential cation channel subfamily C member 3 Peptide, transient receptor potential cation channel, subfamily C, member 3 Peptide, TRPC3 Peptide, Trpc3 Peptide
- Background
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TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. TRPC3 is activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C, and by inositol-1,4,5-triphosphate receptors (ITPR) with bound IP3. TRPC3 may also be activated by internal calcium store depletion.
Alias Symbols: TRP3
Protein Interaction Partner: MX1,NAPA,VAMP2,CALM1,FKBP1A,GNA11,ITPR1,ITPR3,MX1,NAPA,ORAI1,PLCB1,PLCB2,PLCB3,PLCG1,PLCG1,PRKCA,PRKG1,SLC8A1,STX3,TRPC1,TRPC6,VAMP2,ITPR1,ITPR3,TRPC1,TRPC3,TRPC4,TRPC5,TRPC6,TRPC7
Protein Size: 848 - Molecular Weight
- 97 kDa
- Gene ID
- 7222
- NCBI Accession
- NM_003305, NP_003296
- UniProt
- Q13507
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