Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6) (N-Term) Peptide
TRPC6
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRPC6 products
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRPC6 antibody (Catalog #: ARP58718_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))
- Synonyms
- FSGS2 Peptide, TRP6 Peptide, AV025995 Peptide, LLHWJM002 Peptide, LLHWJM003 Peptide, LLHWJM004 Peptide, TRP-6 Peptide, Trrp6 Peptide, mtrp6 Peptide, trp6 Peptide, bZ1P14.9 Peptide, si:rp71-1p14.9 Peptide, trpc6 Peptide, transient receptor potential cation channel subfamily C member 6 Peptide, transient receptor potential cation channel, subfamily C, member 6 Peptide, transient receptor potential cation channel, subfamily C, member 6a Peptide, TRPC6 Peptide, Trpc6 Peptide, trpc6a Peptide, trpc6 Peptide
- Background
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TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Alias Symbols: FLJ11098, FLJ14863, FSGS2, TRP6
Protein Interaction Partner: MX1,FYN,ITPR3,MX1,ORAI1,SRC,TRPC3,TRPC6,TRPM2,FYN,ITPR1,ITPR3,SRC,TRPC1,TRPC2,TRPC3,TRPC4,TRPC5,TRPC6,TRPC7
Protein Size: 931 - Molecular Weight
- 106 kDa
- Gene ID
- 7225
- NCBI Accession
- NM_004621, NP_004612
- UniProt
- Q9Y210
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