Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1) Peptide
CIAO1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CIAO1 products
- CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-WDR39 antibody (Catalog #: ARP38517_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))
- Synonyms
- CG12797 Peptide, Dmel\\CG12797 Peptide, DDBDRAFT_0190506 Peptide, DDBDRAFT_0266672 Peptide, DDB_0190506 Peptide, DDB_0266672 Peptide, CIA1 Peptide, WDR39 Peptide, AW210570 Peptide, Wdr39 Peptide, wdr39 Peptide, zgc:55911 Peptide, zgc:77394 Peptide, CG12797 gene product from transcript CG12797-RA Peptide, WD40 protein Ciao1 Peptide, CIAO1 Peptide, WD40 repeat-containing protein Peptide, cytosolic iron-sulfur assembly component 1 Peptide, cytosolic iron-sulfur protein assembly 1 Peptide, Ciao1 Peptide, cgd1_2230 Peptide, CC1G_05316 Peptide, ciao1 Peptide, CIAO1 Peptide
- Background
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WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Alias Symbols: CIA1, WDR39
Protein Interaction Partner: CCDC7,FAM96A,FAM96B,GOLM1,WT1,CCDC7,FAM96A,FAM96B,GAS8,HEATR2,KIAA1967,MCM5,MLF2,MYO1C,USP11
Protein Size: 339 - Molecular Weight
- 38 kDa
- Gene ID
- 9391
- NCBI Accession
- NM_004804, NP_004795
- UniProt
- O76071
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