Xeroderma Pigmentosum, Complementation Group A (XPA) (C-Term) Peptide
XPA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all XPA products
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-XPA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Synonyms
- CG6358 Peptide, DhR14 Peptide, DhXPA Peptide, DmXPA Peptide, Dmel\\CG6358 Peptide, Dxpa Peptide, EG:EG0007.8 Peptide, XPAC Peptide, XPA_DROME Peptide, Xpa Peptide, dmXPA Peptide, dxpa Peptide, XP1 Peptide, AI573865 Peptide, Xpac Peptide, xpac Peptide, xxpa Peptide, Xeroderma pigmentosum group A-like Peptide, XPA, DNA damage recognition and repair factor Peptide, xeroderma pigmentosum, complementation group A Peptide, xeroderma pigmentosum, complementation group A L homeolog Peptide, Xpac Peptide, XPA Peptide, Xpa Peptide, xpa.L Peptide
- Background
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This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: ATM,ATR,DDB2,ERCC1,ERCC6,GPN1,GTF2E2,GTF2H1,PRKDC,RASSF1,RPA1,RPA2,RPA4,XAB2,EP300,ERCC1,ERCC6,GPN1,GTF2E2,MSH2,MSH3,RPA1,RPA2,RPA4,XAB2
Protein Size: 273 - Molecular Weight
- 31 kDa
- Gene ID
- 7507
- NCBI Accession
- NM_000380, NP_000371
- UniProt
- P23025
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