YY1 Associated Factor 2 (YAF2) Peptide
YAF2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all YAF2 products
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-YAF2 antibody (Catalog #: ARP37341_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- YAF2 (YY1 Associated Factor 2 (YAF2))
- Synonyms
- MGC75686 Peptide, YAF2 Peptide, zgc:136577 Peptide, si:ch211-155a11.5 Peptide, 2810021M11Rik Peptide, YY1 associated factor 2 Peptide, YY1-associated factor 2 Peptide, yaf2 Peptide, YAF2 Peptide, LOC100221270 Peptide, Yaf2 Peptide
- Background
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Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
Alias Symbols: 2810021M11Rik
Protein Size: 179 - Molecular Weight
- 20 kDa
- Gene ID
- 67057
- NCBI Accession
- NM_024189, NP_077151
- UniProt
- Q99LW6
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