Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (Middle Region) Peptide
ZFP36
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all ZFP36 products
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZFP36 antibody (Catalog #: ARP38304_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
- Synonyms
- G0S24 Peptide, GOS24 Peptide, NUP475 Peptide, RNF162A Peptide, TIS11 Peptide, TTP Peptide, zfp-36 Peptide, c3h-1 Peptide, g0s24 Peptide, gos24 Peptide, nup475 Peptide, rnf162a Peptide, tis11 Peptide, ttp Peptide, ZFP36 Peptide, C3H-1 Peptide, Gos24 Peptide, Nup475 Peptide, TIS11D Peptide, TISII Peptide, Tis11 Peptide, Ttp Peptide, Zfp-36 Peptide, ZFP36 ring finger protein Peptide, ZFP36 ring finger protein L homeolog Peptide, tristetraproline Peptide, Tristetraproline Peptide, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth Peptide, zinc finger protein 36 Peptide, ZFP36 Peptide, zfp36.L Peptide, EDI_287240 Peptide, Bm1_42085 Peptide, LOAG_03119 Peptide, zfp36 Peptide, Zfp36 Peptide
- Background
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ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Alias Symbols: G0S24, GOS24, NUP475, RNF162A, TIS11, TTP
Protein Interaction Partner: PTGS2,tax,CCDC85B,EDC3,EXOSC6,EXOSC8,HMGB1,MAPKAPK2,NUP214,SFN,UPF2,XRN1,YWHAB,YWHAG,YWHAH,CCDC85B,NUP214,YWHAB,YWHAH
Protein Size: 326 - Molecular Weight
- 34 kDa
- Gene ID
- 7538
- NCBI Accession
- NM_003407, NP_003398
- UniProt
- P26651
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