Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36) (N-Term) Peptide
ZFP36
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ZFP36 products
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LAPRLGPELS PSPTSPTATS TTPSRYKTEL CRTFSESGRC RYGAKCQFAH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TTP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))
- Synonyms
- G0S24 Peptide, GOS24 Peptide, NUP475 Peptide, RNF162A Peptide, TIS11 Peptide, TTP Peptide, zfp-36 Peptide, c3h-1 Peptide, g0s24 Peptide, gos24 Peptide, nup475 Peptide, rnf162a Peptide, tis11 Peptide, ttp Peptide, ZFP36 Peptide, C3H-1 Peptide, Gos24 Peptide, Nup475 Peptide, TIS11D Peptide, TISII Peptide, Tis11 Peptide, Ttp Peptide, Zfp-36 Peptide, ZFP36 ring finger protein Peptide, ZFP36 ring finger protein L homeolog Peptide, tristetraproline Peptide, Tristetraproline Peptide, similar to Tristetraproline (TTP) (Zinc finger protein 36 homolog) (Zfp-36) (TIS11A protein) (TIS11) (Growth Peptide, zinc finger protein 36 Peptide, ZFP36 Peptide, zfp36.L Peptide, EDI_287240 Peptide, Bm1_42085 Peptide, LOAG_03119 Peptide, zfp36 Peptide, Zfp36 Peptide
- Background
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TTP is a mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. It acts by specifically binding ARE-containing mRNAs and promoting their degradation. It recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). And it plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).
Alias Symbols: ZFP36,G0S24, RNF162A, TIS11A, TTP,
Protein Size: 326 - Molecular Weight
- 34 kDa
- Gene ID
- 7538
- UniProt
- P26651
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