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BCL2 Binding Component 3 (BBC3) Peptide

BBC3
Catalog No. ABIN987669
  • Target See all PUMA (BBC3) products
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Sequence
    One-letter code: EEQWAREIGA QLRRMADDLN AQYER, Three-letter code: {Glu}{Glu}{Gln}{Trp}{Ala}{Arg}{Glu}{Ile}{Gly}{Ala}{Gln}{Leu}{Arg}{Arg}{Met}{Ala}{Asp}{Asp}{Leu}{Asn}{Ala}{Gln}{Tyr}{Glu}{Arg
    Characteristics
    Formula: C128H202N42O43S1
    Purity
    > 95 %
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Storage
    -20 °C
  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Synonyms
    BBC3 Peptide, Puma Peptide, JFY-1 Peptide, JFY1 Peptide, PUMA Peptide, PUMA/JFY1 Peptide, BCL2 binding component 3 Peptide, Bcl-2 binding component 3 Peptide, BBC3 Peptide, Bbc3 Peptide, bbc3 Peptide
    Background
    This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
    Molecular Weight
    3049.3
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