PHF8 Products
(PHD Finger Protein 8 (PHF8))
Categories
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
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Featured PHF8 Categories
PHF8 Antibodies
High quality antibodies with extensive validation data.
PHF8 ELISA Kits
Reliable ELISA kits for a wide range of species.
PHF8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PHF8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN542430
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN7269263
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit
Application
WB, IHC, IP, IHC (p), IF, ChIP, PLA
Validations
- (1)
Cat. No.
ABIN2626773
Quantity
50 μL
Datasheet
Datasheet
Recommended PHF8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958513
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674795
Quantity
96 tests
Datasheet
Datasheet
Recommended PHF8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094532
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3135986
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus
Validations
- (2)
Cat. No.
ABIN2669683
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our PHF8 products
: "Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway." in: Nature communications, Vol. 9, Issue 1, pp. 114, (2018) (PubMed).: "The HIF/PHF8/AR axis promotes prostate cancer progression." in: Oncogenesis, Vol. 5, Issue 12, pp. e283, (2016) (PubMed).
: "PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis." in: Cell research, Vol. 20, Issue 7, pp. 794-801, (2010) (PubMed).
: "Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development." in: Nature, Vol. 466, Issue 7305, pp. 503-7, (2010) (PubMed).
Synonyms and alternative names related to PHF8
PHD finger protein 8 (Phf8), PHD finger protein 8 (PHF8), PHD finger protein 8 (phf8), 9830141C09Rik, JHDM1F, mKIAA1111, MRXSSD, RGD1561065, ZNF422, zPHF8Protein level used designations for PHF8
- histone lysine demethylase PHF8
- jumonji C domain-containing histone demethylase 1F
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