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PHKB Products

(Phosphorylase Kinase, beta (PHKB))

Categories

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].

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Featured PHKB Categories

PHKB Antibodies

High quality antibodies with extensive validation data.

PHKB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PHKB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7163408
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6264179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN562212
Quantity 50 μL
Datasheet Datasheet

Recommended PHKB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648029
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6208955
Quantity 96 tests
Datasheet Datasheet

Recommended PHKB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314920
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3135952
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2728841
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our PHKB products

Oppermann, Gnad, Olsen, Hornberger, Greff, Kéri, Mann, Daub: "Large-scale proteomics analysis of the human kinome." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1751-64, (2009) (PubMed).

Beausoleil, Villén, Gerber, Rush, Gygi: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, (2006) (PubMed).

Wüllrich-Schmoll, Kilimann: "Structure of the human gene encoding the phosphorylase kinase beta subunit (PHKB)." in: European journal of biochemistry / FEBS, Vol. 238, Issue 2, pp. 374-80, (1996) (PubMed).

Synonyms and alternative names related to PHKB

phosphorylase kinase regulatory subunit beta (PHKB), phosphorylase kinase beta (Phkb), phosphorylase kinase regulatory subunit beta (Phkb), AI463271

Protein level used designations for PHKB

  • phosphorylase b kinase regulatory subunit beta
  • phosphorylase kinase beta-subunit
  • phosphorylase kinase subunit beta
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