anti-Human BIM antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended BIM Antibody

Antigen
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) Antibodies
  • bim
  • BAM
  • BIM
  • BOD
  • 1500006F24Rik
  • Bim
  • Bod
  • BimL
  • BIMEL
  • BCL2-like 11
  • BCL2 like 11
  • BCL2-like 11 (apoptosis facilitator)
  • bcl2l11
  • BCL2L11
  • Bcl2l11
Epitope
AA 70-111, pSer87
86
30
15
14
14
14
12
11
10
9
9
9
9
9
8
8
8
8
8
8
7
6
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
442
316
296
11
6
6
4
3
3
1
1
Host
Rabbit
402
18
17
9
6
Clonality
Polyclonal
Conjugate
This BIM antibody is un-conjugated
25
15
12
12
11
11
10
10
10
10
10
10
6
6
6
6
6
6
6
6
6
6
4
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
329
182
114
63
61
37
36
27
25
17
7
5
3
3
2
2
2
2
Options

Available images

Catalog No. ABIN682873
$ 351.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
14.774616 ABIN213909 ICC IHC IHC (p) WB Rabbit IgG Internal Region Polyclonal 0
12.70121 ABIN4284640 ELISA IHC IHC (p) WB Rabbit Polyclonal 7
11.5 ABIN542826 IHC (p) ELISA WB Rabbit Polyclonal 3
7 ABIN205966 IHC IHC (p) WB Rabbit IgG AA 22-40 Polyclonal 0
7 ABIN6652369 IF IHC (p) Rabbit pSer65, pSer69 Polyclonal 2
7 ABIN6653795 ICC IHC (p) WB Rabbit IgG Internal Region Polyclonal 0
7 ABIN6652823 IHC (p) WB Rabbit Ser65 Polyclonal 2
7 ABIN265330 EIA IHC (p) WB Rabbit Polyclonal 0
7 ABIN302792 IF IHC (p) WB Rabbit Polyclonal 0
7 ABIN5648912 ELISA IHC (p) WB Rabbit Polyclonal 0
7 ABIN5648722 IF IHC (p) Rabbit IgG pSer69 Polyclonal 0
7 ABIN5648987 IHC (p) WB Rabbit Polyclonal 0
7 ABIN535340 FACS IF IHC (p) IP WB Rat IgG2b 5-00E-05 0
7 ABIN541395 IHC (p) WB Rabbit Polyclonal 2
7 ABIN535339 FACS IF IHC (p) IP WB Rat IgG2a 14A8 0
6.70121 ABIN5950839 ICC IF IHC IHC (p) IP WB Rabbit IgG AA 1-150 SU0318 0
4 ABIN683518 IF (p) IHC (p) WB Rabbit IgG pSer55 Polyclonal 0
4 ABIN5960193 ELISA IHC (p) WB Rabbit IgG Polyclonal 0
4 ABIN298154 ELISA IHC IHC (p) WB Mouse IgG1 AA 2-198 1C2C8 0
4 ABIN687277 IF (p) IHC (p) WB Rabbit IgG Polyclonal 0

General

Antigen BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) Antibodies
Epitope AA 70-111, pSer87
(86), (30), (15), (14), (14), (14), (12), (11), (10), (9), (9), (9), (9), (9), (8), (8), (8), (8), (8), (8), (7), (6), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(442), (316), (296), (11), (6), (6), (4), (3), (3), (1), (1)
Host Rabbit
(402), (18), (17), (9), (6)
Clonality
Polyclonal
Conjugate This BIM antibody is un-conjugated
(25), (15), (12), (12), (11), (11), (10), (10), (10), (10), (10), (10), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(329), (182), (114), (63), (61), (37), (36), (27), (25), (17), (7), (5), (3), (3), (2), (2), (2), (2)
Pubmed 2 references available
Supplier

Product Details anti-BIM Antibody

Target Details BIM Application Details Handling References for anti-BIM antibody (ABIN682873) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human Bim around the phosphorylation site of Ser87
Isotype IgG
Plasmids, Primers & others

Target Details BIM

Product Details anti-BIM Antibody Application Details Handling References for anti-BIM antibody (ABIN682873) Images back to top
Antigen
Alternative Name Bim (BCL2L11 Antibody Abstract)
Background

Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

Subcellular location: Membrane bound

Synonyms: BAM, BIM, BOD, Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BCL2L11

Gene ID 10018
UniProt O43521
Pathways PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-BIM Antibody Target Details BIM Handling References for anti-BIM antibody (ABIN682873) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-BIM Antibody Target Details BIM Application Details References for anti-BIM antibody (ABIN682873) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-BIM antibody (ABIN682873)

Product Details anti-BIM Antibody Target Details BIM Application Details Handling Images back to top
Product cited in:

Lee, Maeng, Kang, Choi, Oh, Ju, Yune: "Valproic acid protects motor neuron death by inhibiting oxidative stress and endoplasmic reticulum stress-mediated cytochrome C release after spinal cord injury." in: Journal of neurotrauma, Vol. 31, Issue 6, pp. 582-94, 2014 Method employed by authors: Western Blotting (WB), Western Blotting (WB)

Gogada, Yadav, Liu, Tang, Zhang, Schneider, Seshadri, Sun, Aldaz, Tang, Chandra: "Bim, a proapoptotic protein, up-regulated via transcription factor E2F1-dependent mechanism, functions as a prosurvival molecule in cancer." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 368-81, 2013

Images

Product Details anti-BIM Antibody Target Details BIM Application Details Handling References for anti-BIM antibody (ABIN682873) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 70-111), (pSer87) antibody (ABIN682873) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti phospho-Bim(S...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) (AA 70-111), (pSer87) antibody (ABIN682873) Formalin-fixed and paraffin embedded mouse intestine labeled with Rabbit Anti-Bim(Ser...