anti-Rat (Rattus) MAPKAP1 antibody for ELISA

Recommended MAPKAP1 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
  • CG10105
  • Dmel\\CG10105
  • dSin1
  • sin1
  • MAPKAP1
  • im:7143088
  • si:ch73-242f23.1
  • mip1
  • sin1b
  • sin1g
  • MGC53034
  • JC310
  • MIP1
  • SIN1
  • SIN1b
  • SIN1g
  • AI591529
  • D230039K05Rik
  • Sin1
  • SAPK-interacting protein 1
  • mitogen-activated protein kinase associated protein 1
  • mitogen-activated protein kinase associated protein 1 L homeolog
  • Sin1
  • MAPKAP1
  • mapkap1
  • Mapkap1
  • mapkap1.L
Reactivity
Human, Mouse (Murine), Rat (Rattus)
87
46
40
13
10
5
3
3
3
2
1
1
1
Host
Rabbit
89
Clonality
Polyclonal
Conjugate
This MAPKAP1 antibody is un-conjugated
2
2
2
2
2
2
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
81
38
37
19
12
4
2
2
2
2
Supplier
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Available images

Catalog No. ABIN6265084
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1002804 IHC ELISA WB Rabbit IgG N-Term Log in to see Polyclonal 4
1 ABIN1002803 IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 4
1 ABIN4353812 ELISA IHC IHC (p) WB Rabbit Center Log in to see Polyclonal 0
1 ABIN4353811 ELISA ICC IF IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN1031450 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN1030995 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
1 ABIN5701108 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5701107 ELISA IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2938571 ELISA IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1088841 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1887685 IHC ELISA WB Rabbit Center Log in to see Polyclonal 0
1 ABIN1888099 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN5903460 ELISA IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN5903461 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(87), (46), (40), (13), (10), (5), (3), (3), (3), (2), (1), (1), (1)
Host Rabbit
(89)
Clonality
Polyclonal
Conjugate This MAPKAP1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
(81), (38), (37), (19), (12), (4), (2), (2), (2), (2)
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Product Details anti-MAPKAP1 Antibody

Target Details MAPKAP1 Application Details Handling Images
Specificity SIN1 Antibody detects endogenous levels of total SIN1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Immunogen A synthesized peptide derived from human SIN1
Isotype IgG
Plasmids, Primers & others

Target Details MAPKAP1

Product Details anti-MAPKAP1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name SIN1 (MAPKAP1 Antibody Abstract)
Background

Description: Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Within mTORC2, MAPKAP1 is required for complex formation and mTORC2 kinase activity. MAPKAP1 inhibits MAP3K2 by preventing its dimerization and autophosphorylation. Inhibits HRAS and KRAS signaling. Enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription. Involved in ciliogenesis, regulates cilia length through its interaction with CCDC28B independently of mTORC2 complex.

Gene: MAPKAP1

Molecular Weight 59 kDa
Gene ID 79109
UniProt Q9BPZ7
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events

Application Details

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Handling Images back to top
Application Notes WB 1:1000-3000 IHC 1:200
Restrictions For Research Use only

Handling

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-MAPKAP1 Antibody Target Details MAPKAP1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) antibody (ABIN6265084) Western blot analysis SIN1 using K562 whole cell lysates
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) antibody (ABIN6265084) ABIN6277739 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was for...